Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 8/20 | 0.55 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | MASP2 | O00187 | 3/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306839 | 0.84 | NAMPT (0.47) | VNN1NAMPTMASP2 | |
| SCHEMBL4309422 | 0.84 | NAMPT (0.43) | VNN1NAMPTMASP2 | |
| SCHEMBL4308748 | 0.84 | MASP2 (0.44) | VNN1NAMPTMASP2 | |
| SCHEMBL4303439 | 0.83 | NAMPT (0.53) | NAMPTMASP2 | |
| SCHEMBL4304420 | 0.81 | MEN1 (0.47) | NAMPTMASP2 | |
| SCHEMBL3148809 | 0.81 | VNN1 (0.55) | VNN1NAMPTMASP2ERCC1ERCC4 | |
| SCHEMBL4309586 | 0.81 | F2 (0.45) | VNN1NAMPT | |
| SCHEMBL4308746 | 0.78 | NAMPT (0.41) | NAMPTMASP2 | |
| SCHEMBL4305726 | 0.78 | NAMPT (0.45) | VNN1NAMPTMASP2 | |
| SCHEMBL4307976 | 0.78 | NAMPT (0.49) | NAMPTMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |