Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312613 | 0.87 | SMN1; SMN2 (0.45) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL4308748 | 0.86 | MASP2 (0.44) | MEN1KMT2AALDH1A1CDK8MASP2 | |
| SCHEMBL4306839 | 0.84 | NAMPT (0.47) | MEN1KMT2ALMNACDK8MASP2 | |
| SCHEMBL4309422 | 0.84 | NAMPT (0.43) | CDK8MASP2NAMPT | |
| SCHEMBL4303439 | 0.83 | NAMPT (0.53) | MEN1KMT2APOLBMASP2NAMPT | |
| SCHEMBL4309586 | 0.81 | F2 (0.45) | MEN1KMT2APOLBCDK8NAMPT | |
| SCHEMBL4312874 | 0.81 | VNN1 (0.55) | MASP2NAMPT | |
| SCHEMBL3154324 | 0.81 | ROCK2 (0.48) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL4309246 | 0.79 | MEN1 (0.43) | MEN1KMT2APOLBLMNAMASP2 | |
| SCHEMBL4305726 | 0.78 | NAMPT (0.45) | MEN1KMT2AMASP2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |