Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551628 | 0.88 | L3MBTL1 (0.46) | L3MBTL1MAPTHPGDATMTDP1 | |
| SCHEMBL8317233 | 0.82 | DRD2 (0.50) | L3MBTL1HPGDDRD2DRD4TP53 | |
| SCHEMBL7885446 | 0.80 | L3MBTL1 (0.46) | L3MBTL1MAPTHPGDATMDRD2 | |
| SCHEMBL5805893 | 0.80 | MAPT (0.51) | L3MBTL1MAPTHPGDATMHDAC6 | |
| SCHEMBL19896311 | 0.80 | MAPT (0.51) | L3MBTL1MAPTHPGDATMHDAC6 | |
| SCHEMBL6427364 | 0.79 | CYP1A2 (0.56) | L3MBTL1MAPTHPGDATMHDAC6 | |
| SCHEMBL3083050 | 0.78 | L3MBTL1 (0.50) | L3MBTL1MAPTHPGDATMDRD2 | |
| SCHEMBL4329339 | 0.78 | KCNA3 (0.80) | KCNA3DRD2DRD4DRD3HDAC3 | |
| SCHEMBL7562011 | 0.77 | MAPT (0.52) | L3MBTL1MAPTHPGDATMDRD2 | |
| SCHEMBL19175412 | 0.77 | ALDH1A1 (0.47) | L3MBTL1MAPTHPGDATMDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517896-B2 | Aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2009-04-14 | — | — | US | disclosed |