Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19896311 | 0.91 | MAPT (0.51) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5805893 | 0.91 | MAPT (0.51) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4309191 | 0.88 | KCNA3 (0.59) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7885446 | 0.87 | L3MBTL1 (0.46) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6427364 | 0.86 | CYP1A2 (0.56) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8317233 | 0.85 | DRD2 (0.50) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3083050 | 0.84 | L3MBTL1 (0.50) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19175412 | 0.83 | ALDH1A1 (0.47) | L3MBTL1TP53MAPTNPSR1LMNA | |
| SCHEMBL7562011 | 0.83 | MAPT (0.52) | L3MBTL1CYP1A2CYP2C9TSHRMAPT | |
| SCHEMBL19167176 | 0.82 | L3MBTL1 (0.50) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |