Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009200 | 0.87 | ABCB1 (0.40) | TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2 | |
| SCHEMBL4006080 | 0.86 | CYP3A4 (0.39) | MAPTTP53ALDH1A1 | |
| SCHEMBL4005126 | 0.85 | HSD11B1 (0.34) | MAPTALDH1A1 | |
| SCHEMBL4301800 | 0.85 | DDR1 (0.39) | SLC6A9DDR1LMNAMAPTTP53 | |
| SCHEMBL4295046 | 0.83 | SLC6A9 (0.41) | SLC6A9MAPT | |
| SCHEMBL4003450 | 0.83 | HCRTR1 (0.36) | MAPT | |
| SCHEMBL4009205 | 0.83 | ITGB1 (0.38) | MAPT | |
| SCHEMBL4006854 | 0.83 | ALDH1A1 (0.37) | LMNAMAPTTP53ALDH1A1 | |
| SCHEMBL4006907 | 0.81 | MEN1 (0.41) | LMNAMAPTCNR2ALDH1A1 | |
| SCHEMBL4002243 | 0.81 | ALDH1A1 (0.37) | LMNAMAPTCNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |