Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 14/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14457466 | 0.87 | AGXT (0.36) | AGXTPDE10ASHMT2BRS3 | |
| SCHEMBL4305889 | 0.85 | AGXT (0.34) | AGXTPDE10AHSP90AA1SHMT2BRS3 | |
| SCHEMBL4305125 | 0.85 | PDE10A (0.44) | AGXTPDE10AHSP90AA1HSP90AB1SHMT2 | |
| SCHEMBL14457590 | 0.84 | AGXT (0.34) | AGXTPDE10ASHMT2 | |
| SCHEMBL4311415 | 0.84 | PDE10A (0.37) | AGXTPDE10AHSP90AA1HSP90AB1 | |
| SCHEMBL4309284 | 0.79 | EIF4E (0.36) | — | |
| SCHEMBL4309065 | 0.78 | KCNH2 (0.47) | — | |
| SCHEMBL5066799 | 0.76 | SHMT2 (0.35) | AGXTPDE10AHSP90AA1HSP90AB1TRAP1 | |
| SCHEMBL4308839 | 0.74 | EIF4E (0.34) | — | |
| SCHEMBL4304668 | 0.74 | FFAR1 (0.42) | SHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | CIBA CORP. | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090044345-A1 | Use of Metal Complex Compounds as Oxidation Catalysts | MT-CO2, MT-CO1, SOD1 | AGXT 1388/4885PDE10A 3997/4885HSP90AA1 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.