SCHEMBL4309952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4306576	0.85	RPS6KB1 (0.33)	CES2CES1APPPTGS2RPS6KB1
	SCHEMBL4310334	0.85	PTGS2 (0.39)	PTGS2
	SCHEMBL13667413	0.82	CYP1A2 (0.38)	—
	SCHEMBL4321687	0.82	CYP1A2 (0.38)	—
	SCHEMBL13667412	0.82	CYP1A2 (0.38)	—
	SCHEMBL4306763	0.82	KIF11 (0.41)	CES2CES1AKT1
	SCHEMBL13667414	0.82	TNF (0.38)	RPS6KB1
	SCHEMBL4309855	0.82	TNF (0.38)	RPS6KB1
	SCHEMBL13667427	0.82	TNF (0.38)	RPS6KB1
	SCHEMBL4308035	0.81	ADRA1D (0.39)	IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.