Encecalin

Encecalin

SCHEMBL4310132

COc1cc2c(cc1C(C)=O)C=CC(C)(C)O2

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.68
CYP3A4 P08684 1/20 0.68
HPGD P15428 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
COXFA4 O00483 1/20 0.46
HIF1A Q16665 1/20 0.46
ODC1 P11926 1/20 0.45
PTPN1 P18031 1/20 0.45
HSP90AA1 P07900 1/20 0.44
XDH P47989 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prococene Ii SCHEMBL119925 0.81 ODC1 (0.54) ALDH1A1CYP3A4HPGDTDP1HIF1A
SCHEMBL546770 0.81 ALDH1A1 (0.48) ALDH1A1CYP3A4HPGDTDP1COXFA4
Demethylencecalin SCHEMBL29903823 0.81 ALDH1A1 (1.00) ALDH1A1CYP3A4HPGDTDP1PTPN1
Demethylencecalin SCHEMBL31238098 0.81 ALDH1A1 (1.00) ALDH1A1CYP3A4HPGDTDP1PTPN1
SCHEMBL29404075 0.79 ALDH1A1 (0.54) ALDH1A1CYP3A4HPGDTDP1HIF1A
SCHEMBL545855 0.79 ALDH1A1 (0.54) ALDH1A1CYP3A4HPGDTDP1HIF1A
SCHEMBL11012720 0.78 TLR3 (0.48) COXFA4HIF1AODC1
SCHEMBL8881498 0.76 ODC1 (0.49) HIF1AODC1
SCHEMBL10508119 0.75 ODC1 (0.46) HIF1AODC1
SCHEMBL8882520 0.75 ODC1 (0.49) ALDH1A1CYP3A4HPGDTDP1ODC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034186-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2026-02-05 US disclosed
US-20260027136-A1 CANNABIS BASED THERAPEUTIC AND METHOD OF USE YUZU LV LLC (US) 2026-01-29 US disclosed
US-12458653-B2 Cannabis based therapeutic and method of use YUZU LV LLC (US) 2025-11-04 US disclosed
US-12427176-B2 Enriched mineral pitch resin products and methods of manufacturing enriched mineral pitch resin products RIZUN NODARI (US) 2025-09-30 US disclosed
US-12303488-B2 Cannabis based therapeutic and method of use YUZU LV LLC (US) 2025-05-20 US disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
EP-4417252-A2 CANNABIS BASED THERAPEUTIC AND METHOD OF USE Yuzu LV LLC (US) 2024-08-21 EP disclosed
US-20240216457-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-07-04 US disclosed
US-20240216456-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-07-04 US disclosed
US-20240207342-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-06-27 US disclosed
US-20230293480-A1 CANNABIS BASED THERAPEUTIC AND METHOD OF USE YUZU LV LLC 2023-09-21 US disclosed
US-20230293555-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND FLAVANONES YUZU LV LLC 2023-09-21 US disclosed
US-11684604-B2 Cannabis based therapeutic and method of use YUZU LV LLC (US) 2023-06-27 US disclosed
US-20220387537-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2022-12-08 US disclosed
US-20210023044-A1 CANNABIS BASED THERAPEUTIC AND METHOD OF USE YUZU LV LLC 2021-01-28 US disclosed
US-20170042823-A1 CO-ENCAPSULATION OF ANTIMICROBIALS AND ADJUVANTS IN NANOCARRIERS UNIV PRINCETON (US) 2017-02-16 US disclosed
WO-2009134112-A1 PHARMACEUTICAL FORMULATION THAT COMPRISES A BLEACHED EXTRACT OF AGERATINA PICHINCHENSIS FOR TREATING ONYCHOMYCOSIS ROMERO CERECERO OFELIA (MX) 2009-11-05 WO disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed
EP-0028449-B1 CHROMANOL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION COMPRISING THEM BEECHAM GROUP PLC (GB) 1983-07-20 EP disclosed
EP-0028449-A1 Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them BEECHAM GROUP PLC (GB) 1981-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11684604-B2 Cannabis based therapeutic and method of use CNR2, CNR1, OPRK1 ALDH1A1 3206/4885CYP3A4 2613/4885HPGD 1556/4885
US-20260027136-A1 CANNABIS BASED THERAPEUTIC AND METHOD OF USE CNR1, CNR2, OPRM1 ALDH1A1 1420/4885CYP3A4 1136/4885HPGD 696/4885
US-20260034186-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS TRPV1, SOST, RUNX1 ALDH1A1 4768/4885CYP3A4 1979/4885HPGD 1580/4885
US-20210023044-A1 CANNABIS BASED THERAPEUTIC AND METHOD OF USE CNR2, CNR1, OPRK1 ALDH1A1 3206/4885CYP3A4 2613/4885HPGD 1556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.