Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188833 | 1.00 | LMNA (0.52) | LMNAFKBP1ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL3920618 | 0.86 | LMNA (0.51) | LMNAFKBP1ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL9042461 | 0.84 | L3MBTL1 (0.51) | FKBP1ATSHRALDH1A1L3MBTL1KMT2A | |
| SCHEMBL6879707 | 0.84 | L3MBTL1 (0.51) | FKBP1ATSHRALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10904190 | 0.84 | L3MBTL1 (0.51) | FKBP1ATSHRALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10870111 | 0.83 | MCOLN3 (0.54) | LMNATSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8268313 | 0.79 | HTR2A (0.46) | FKBP1ATSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7450743 | 0.78 | ITGB1 (0.48) | SMN1; SMN2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16431386 | 0.77 | TSHR (0.44) | LMNATSHRALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL16220206 | 0.77 | ACHE (0.50) | LMNAFKBP1AALDH1A1SMN1; SMN2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113922-A1 | IMPROVED METHOD FOR PREPARING N-(BENZENESULFONYL)-L-PROLYL- L-O-(1-PYRROLIDINYLCARBONYL)TYROSINE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2021-06-17 | — | — | WO | disclosed |
| US-8084448-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-12-27 | — | — | US | disclosed |
| US-20090181928-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181928-A1 | ORGANIC COMPOUNDS | PTPRS, PTPRO, PTPRC | LMNA 4825/4885FKBP1A 766/4885TSHR 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.