Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042461 | 1.00 | L3MBTL1 (0.51) | L3MBTL1MAPK1GAAHPGDTSHR | |
| SCHEMBL10904190 | 1.00 | L3MBTL1 (0.51) | L3MBTL1MAPK1GAAHPGDTSHR | |
| SCHEMBL27934045 | 0.95 | PSEN1 (0.50) | L3MBTL1MAPK1GAAHPGDTSHR | |
| SCHEMBL12005682 | 0.87 | GAA (0.50) | L3MBTL1MAPK1GAAHPGDTSHR | |
| SCHEMBL4310883 | 0.84 | LMNA (0.52) | L3MBTL1TSHRACHEALDH1A1FKBP1A | |
| SCHEMBL7188833 | 0.84 | LMNA (0.52) | L3MBTL1TSHRACHEALDH1A1FKBP1A | |
| SCHEMBL19989324 | 0.81 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL19989322 | 0.81 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL23630333 | 0.81 | MCOLN3 (0.50) | L3MBTL1MCOLN3NPSR1ACHEALDH1A1 | |
| SCHEMBL8207819 | 0.80 | MMP1 (0.59) | MAPK1GAATSHRALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091407-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLP (US) | 2011-07-28 | — | — | WO | disclosed |