Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327800 | 0.79 | AGXT (0.46) | AOC3 | |
| SCHEMBL4940681 | 0.78 | IKBKB (0.56) | ERN1AOC3PARP1DHODHCFD | |
| SCHEMBL172996 | 0.78 | CFD (0.61) | ERN1AOC3PARP1DHODHCFD | |
| SCHEMBL2431097 | 0.77 | PARP1 (0.64) | ERN1PARP1DHODHCCNT1CCND1 | |
| SCHEMBL31422694 | 0.77 | PARP1 (0.64) | ERN1PARP1DHODHCCNT1CCND1 | |
| SCHEMBL12269244 | 0.76 | ERN1 (0.49) | ERN1AOC3PARP1DHODHCFD | |
| SCHEMBL2635745 | 0.76 | FOLH1 (0.56) | — | |
| SCHEMBL172981 | 0.76 | BCL2 (0.61) | ERN1AOC3PARP1DHODHCFD | |
| SCHEMBL28745456 | 0.76 | FOLH1 (0.56) | — | |
| SCHEMBL4944580 | 0.76 | PARP1 (0.50) | ERN1AOC3PARP1DHODHCFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |