Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.42 |
| ▸ | UBE2M | P61081 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969454 | 0.89 | HSD11B1 (0.44) | CCR5KCNH2PGRCYP2D6CYP2C9 | |
| SCHEMBL5969537 | 0.89 | CCR5 (0.49) | CCR5KCNH2DCUN1D1UBE2MCYP3A4 | |
| SCHEMBL4312474 | 0.88 | MEN1 (0.44) | CCR5KCNH2DCUN1D1UBE2MCYP3A4 | |
| SCHEMBL5969609 | 0.88 | CCR5 (0.47) | CCR5KCNH2DCUN1D1UBE2MCYP3A4 | |
| SCHEMBL4306650 | 0.88 | MEN1 (0.52) | TACR1JAK2 | |
| SCHEMBL5969490 | 0.87 | LMNA (0.48) | CCR5KCNH2PGRCYP2D6CYP2C9 | |
| SCHEMBL5969485 | 0.85 | UBE2M (0.39) | CCR5KCNH2DCUN1D1UBE2MTACR1 | |
| SCHEMBL5969498 | 0.85 | CHRM1 (0.43) | CCR5KCNH2DCUN1D1UBE2MPGR | |
| SCHEMBL5969544 | 0.83 | S1PR1 (0.45) | CCR5KCNH2PGRCYP2D6CYP2C9 | |
| SCHEMBL5969511 | 0.83 | CETP (0.45) | CCR5KCNH2DCUN1D1UBE2MPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556045-B1 | 4-AMINOPIPERIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB SA (BE) | 2006-08-02 | — | — | EP | claimed |