Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745901 | 0.76 | CYP1A2 (0.39) | CYP1A2CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL455640 | 0.75 | CYP2A6 (0.39) | CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL7843943 | 0.68 | CYP1A2 (0.54) | CYP1A2CYP2A6KIF11TRPA1NPC1 | |
| SCHEMBL347592 | 0.67 | CYP2A6 (0.80) | CYP1A2CYP2A6KIF11TRPA1NPC1 | |
| SCHEMBL29407167 | 0.67 | CYP2A6 (0.80) | CYP1A2CYP2A6KIF11TRPA1NPC1 | |
| SCHEMBL1371504 | 0.67 | CYP2A6 (0.57) | CYP1A2CYP2A6KIF11TRPA1NPC1 | |
| SCHEMBL598696 | 0.67 | CYP1A2 (0.69) | CYP1A2CYP2A6KIF11ALDH1A1GAA | |
| SCHEMBL3159449 | 0.67 | NCEH1 (0.37) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1225845 | 0.67 | ALDH1A1 (0.37) | CYP1A2RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL7657320 | 0.65 | CYP1A2 (0.50) | CYP1A2CYP2A6KIF11TRPA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569694-B2 | Coumarin compound, material for light emitting device and organic electroluminescent device | CHISSO CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | JNC CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | TRPA1, CYP3A4, UGT1A10 | CYP1A2 18/4885CYP2A6 294/4885KIF11 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.