Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129180 | 0.88 | KDM4E (0.44) | RAPGEF4ALDH1A1KDM4ECA1CA2 | |
| SCHEMBL27388788 | 0.80 | CA1 (0.48) | RAPGEF4ALDH1A1KDM4ECA1CA2 | |
| SCHEMBL11046134 | 0.80 | ALDH1A1 (0.34) | ALDH1A1CA1CA2TRPV4CA12 | |
| SCHEMBL1037698 | 0.80 | ALDH1A1 (0.39) | RAPGEF4ALDH1A1KDM4EFFAR4TRPV4 | |
| SCHEMBL7526380 | 0.79 | TRPV4 (0.34) | RAPGEF4ALDH1A1TRPV4 | |
| SCHEMBL24270004 | 0.78 | ACLY (0.33) | ALDH1A1CA1CA2TRPV4LMNA | |
| SCHEMBL3767120 | 0.78 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4ECA1CA2 | |
| SCHEMBL22980305 | 0.78 | KDM4E (0.38) | RAPGEF4ALDH1A1KDM4ECA1CA2 | |
| SCHEMBL28285675 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4ETRPV4LMNAMAPT | |
| SCHEMBL2884819 | 0.77 | CA1 (0.42) | RAPGEF4ALDH1A1KDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557153-B2 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP BV (NL) | 2009-07-07 | — | — | US | disclosed |
| EP-1951788-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | General Electric Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007053500-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100059-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-03 | — | — | US | disclosed |