Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13172256 | 0.84 | HTR1A (0.63) | ALDH1A1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL4323598 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTRAB9AHPGDHTT | |
| SCHEMBL4327763 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTRAB9AHPGDHTT | |
| SCHEMBL13626630 | 0.81 | HTR1A (0.61) | ALDH1A1MAPTSMN1; SMN2POLBHTR1A | |
| SCHEMBL4311261 | 0.81 | HTR1A (0.61) | ALDH1A1MAPTSMN1; SMN2POLBHTR1A | |
| SCHEMBL4454995 | 0.73 | HTR1A (0.81) | ALDH1A1MAPTRAB9AHPGDPOLB | |
| SCHEMBL13626236 | 0.73 | HTR1A (0.81) | ALDH1A1MAPTRAB9AHPGDPOLB | |
| SCHEMBL4454997 | 0.73 | HTR1A (0.81) | ALDH1A1MAPTRAB9AHPGDPOLB | |
| SCHEMBL1674417 | 0.73 | FAAH (0.62) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4323726 | 0.73 | HTR1A (0.74) | POLBHTR1AADORA3CCKARHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | claimed |