Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316447 | 1.00 | KMT2A (0.49) | KMT2AALDH1A1MEN1GAAHTT | |
| SCHEMBL13783800 | 1.00 | KMT2A (0.49) | KMT2AALDH1A1MEN1GAAHTT | |
| SCHEMBL13784018 | 0.91 | NPSR1 (0.56) | KMT2AALDH1A1GAAHTTMAPT | |
| SCHEMBL4316894 | 0.91 | NPSR1 (0.56) | KMT2AALDH1A1GAAHTTMAPT | |
| SCHEMBL4316889 | 0.91 | NPSR1 (0.56) | KMT2AALDH1A1GAAHTTMAPT | |
| SCHEMBL4451828 | 0.85 | FPR1 (0.46) | KMT2AALDH1A1MEN1GAAHTT | |
| SCHEMBL13783918 | 0.85 | FPR1 (0.46) | KMT2AALDH1A1MEN1GAAHTT | |
| SCHEMBL4451822 | 0.85 | FPR1 (0.46) | KMT2AALDH1A1MEN1GAAHTT | |
| SCHEMBL13783960 | 0.83 | NPC1 (0.41) | KMT2AALDH1A1MEN1GAAHTT | |
| SCHEMBL13783891 | 0.80 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |