Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451828 | 1.00 | FPR1 (0.46) | FPR1FPR2MGAT2GAAALDH1A1 | |
| SCHEMBL13783918 | 1.00 | FPR1 (0.46) | FPR1FPR2MGAT2GAAALDH1A1 | |
| SCHEMBL4316449 | 0.85 | KMT2A (0.49) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13783800 | 0.85 | KMT2A (0.49) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4316447 | 0.85 | KMT2A (0.49) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13784018 | 0.84 | NPSR1 (0.56) | GAAALDH1A1KMT2AL3MBTL1NPC1 | |
| SCHEMBL4316894 | 0.84 | NPSR1 (0.56) | GAAALDH1A1KMT2AL3MBTL1NPC1 | |
| SCHEMBL4316889 | 0.84 | NPSR1 (0.56) | GAAALDH1A1KMT2AL3MBTL1NPC1 | |
| SCHEMBL13783960 | 0.81 | NPC1 (0.41) | GAAALDH1A1MEN1KMT2ADRD2 | |
| SCHEMBL13783891 | 0.78 | ALDH1A1 (0.44) | GAAALDH1A1MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |