Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3626241 | 0.99 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1HTR6DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1379686 | 0.90 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1HTR6DRD2DRD3 | |
| SCHEMBL3616769 | 0.84 | KEAP1 (0.64) | HTR6MEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3623176 | 0.82 | KEAP1 (0.64) | HTR6HTR2AMEN1KMT2AKEAP1 | |
| SCHEMBL1380665 | 0.82 | HTR6 (0.52) | HTR6HTR2AKEAP1NFE2L2NMT1 | |
| SCHEMBL3626154 | 0.82 | HTR6 (0.55) | HTR6HTR2AKEAP1NFE2L2SQSTM1 | |
| SCHEMBL3622053 | 0.82 | HKDC1 (0.56) | HTR6HTR2AHTR2CKMT2AKEAP1 | |
| SCHEMBL1377079 | 0.81 | KEAP1 (0.67) | HTR6GAAKEAP1NFE2L2SQSTM1 | |
| Hydrochloric Acid SCHEMBL1379130 | 0.81 | KEAP1 (0.63) | HTR6HTR2AMEN1KMT2AKEAP1 | |
| Hydrochloric Acid SCHEMBL1377991 | 0.81 | HKDC1 (0.55) | HTR6HTR2AHTR2CKMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572787-B2 | Substituted naphthalene sulfonamides | BIOVITRUM AB (SE) | 2009-08-11 | — | — | US | claimed |