SCHEMBL4319648

SCHEMBL4319648

O=C1c2cccc(F)c2C(=O)N1c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA1A P0DMV8 1/20 0.67
PABPC1 P11940 1/20 0.67
ALPL P05186 1/20 0.52
GRM1 Q13255 1/20 0.49
GRM4 Q14833 1/20 0.49
ALDH1A1 P00352 3/20 0.49
POLB P06746 2/20 0.49
ADORA2A P29274 1/20 0.49
KMT2A Q03164 3/20 0.48
USP2 O75604 2/20 0.48
MAPT P10636 2/20 0.48
HTT P42858 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 2/20 0.48
LMNA P02545 1/20 0.48
TNNI3 P19429 1/20 0.48
TNNT2 P45379 1/20 0.48
TNNC1 P63316 1/20 0.48
KDM4E B2RXH2 2/20 0.47
KEAP1 Q14145 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1736349 0.93 HSPA1A (0.56) HSPA1APABPC1ALPLGRM1GRM4
SCHEMBL1735194 0.89 HSPA1A (0.53) HSPA1APABPC1ALPLGRM1GRM4
SCHEMBL9113912 0.81 PGR (0.46) HSPA1APABPC1ALPLGRM1GRM4
SCHEMBL31259838 0.80 HSPA1A (1.00) HSPA1APABPC1ALDH1A1POLBADORA2A
SCHEMBL11513204 0.80 HSPA1A (1.00) HSPA1APABPC1ALDH1A1POLBADORA2A
SCHEMBL9241571 0.79 BRD4 (0.56) HSPA1APABPC1GRM1GRM4ALDH1A1
SCHEMBL1500541 0.79 HSPA1A (0.67) HSPA1APABPC1GRM1GRM4ALDH1A1
SCHEMBL9237801 0.79 HSPA1A (0.67) HSPA1APABPC1ALDH1A1POLBADORA2A
SCHEMBL1828224 0.79 HSPA1A (0.67) HSPA1APABPC1ALDH1A1POLBADORA2A
N-Phenyl-Phthalimide SCHEMBL123618 0.78 KMT2A (0.68) HSPA1APABPC1ALDH1A1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5264588-A Reaction of chlorophthalic acid with aniline OCCIDENTAL CHEMICAL CORPORATION (US) 1993-11-23 US claimed
US-5208346-A Simplified process for the preparation of aromatic bismides GENERAL ELECTRIC COMPANY (US) 1993-05-04 US claimed
CN-104311825-B Phenolphthalein type copolyimide and preparation method thereof 中国科学院宁波材料技术与工程研究所 2017-05-17 CN disclosed
CN-105985521-A Polybenzimidazole imide and preparation method thereof 中国科学院宁波材料技术与工程研究所 2016-10-05 CN disclosed
CN-1867592-B Process for fractionation/concentration to reduce the polydispersivity of polymers SABIC INNOVATIVE PLASTICS IP 2012-10-03 CN disclosed
US-7605222-B2 Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-20 US disclosed
US-20070043203-A1 Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units GENERAL ELECTRIC COMPANY (US) 2007-02-22 US disclosed
CN-1867592-A Process for fractionation/concentration to reduce the polydispersivity of polymers GEN ELECTRIC (US) 2006-11-22 CN disclosed
CN-1077191-A PROCESS FOR SELECTIVE HYDRODEFLUORINATION OCCIDENTAL CHEM CO (US) 1993-10-13 CN disclosed
US-5208346-A Simplified process for the preparation of aromatic bismides GENERAL ELECTRIC COMPANY (US) 1993-05-04 US disclosed
US-4960903-A Aromatic compounds having sulfonyl groups TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1990-10-02 US disclosed
EP-0233409-B1 AROMATIC SULFONYL COMPOUNDS Tonen Corporation (JP) 1990-09-26 EP disclosed
EP-0233409-A2 Aromatic sulfonyl compounds Tonen Corporation (JP) 1987-08-26 EP disclosed