Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319648 | 0.89 | HSPA1A (0.67) | HSPA1APABPC1GRM1TYMSGRM4 | |
| SCHEMBL1736349 | 0.89 | HSPA1A (0.56) | HSPA1APABPC1GRM1GRM4ALPL | |
| SCHEMBL9468815 | 0.80 | HSPA1A (0.80) | HSPA1APABPC1TYMSNR1H3SCN2A | |
| SCHEMBL9241571 | 0.79 | BRD4 (0.56) | HSPA1APABPC1GRM1GRM4NR1H3 | |
| SCHEMBL1736347 | 0.79 | HSPA1A (0.53) | HSPA1APABPC1GRM1TYMSGRM4 | |
| SCHEMBL725608 | 0.78 | NR1H3 (0.67) | HSPA1APABPC1NR1H3SCN2ANPC1 | |
| SCHEMBL2890258 | 0.76 | HSPA1A (0.54) | HSPA1APABPC1TYMSNR1H3PGR | |
| SCHEMBL19834886 | 0.76 | DPP4 (0.55) | GRM1GRM4ALPLADORA2A | |
| SCHEMBL29631855 | 0.76 | GRM1 (0.47) | HSPA1APABPC1GRM1GRM4ALPL | |
| SCHEMBL11845327 | 0.75 | CTDSP1 (0.67) | HSPA1APABPC1TYMSNR1H3SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102160-B1 | CARBAZOLYL MONOMERS AND POLYMERS | GEN ELECTRIC (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110262920-A1 | METHODS FOR PREDICTING SURVIVAL IN CANCER PATIENTS | CITY OF HOPE | 2011-10-27 | — | — | US | disclosed |
| EP-2102159-B1 | BIS-CARBAZOLE MONOMERS AND POLYMERS | GEN ELECTRIC (US) | 2011-06-22 | — | — | EP | disclosed |
| US-7851579-B2 | Monomers comprising carbazole units and polymers, dendrimers, and hyper-branched materials derived therefrom; OLEDs having device quantum efficiencies, while still maintaining the potential for the molecules to host red, green, and blue emissive complexes | GENERAL ELECTRIC COMPANY (US) | 2010-12-14 | — | — | US | disclosed |
| US-7635777-B2 | Carbazolyl monomers and polymers | GENERAL ELECTRIC COMPANY (US) | 2009-12-22 | — | — | US | disclosed |
| US-20080145665-A1 | polyesters, polyethers, polycarbonates, polyestercarbonates, polyetherketones, or polyethersulfones for use in organic light emitters; quantum efficiencies | GENERAL ELECTRIC COMPANY (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080138625-A1 | CARBAZOLYL MONOMERS AND POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080135806-A1 | CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138625-A1 | CARBAZOLYL MONOMERS AND POLYMERS | CBR3, C1S, C3AR1 | HSPA1A 4531/4885PABPC1 2834/4885GRM1 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.