SCHEMBL1736349

SCHEMBL1736349

O=C1c2cccc(F)c2C(=O)N1c1ccc(N2C(=O)c3cccc(F)c3C2=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSPA1A P0DMV8 1/20 0.56
PABPC1 P11940 1/20 0.56
ADORA2A P29274 1/20 0.56
GRM1 Q13255 2/20 0.54
GRM4 Q14833 1/20 0.54
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ALPL P05186 1/20 0.48
AHR P35869 1/20 0.47
ALDH1A1 P00352 1/20 0.46
SCN2A Q99250 3/20 0.44
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
PGR P06401 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4319648 0.93 HSPA1A (0.67) HSPA1APABPC1ADORA2AGRM1GRM4
SCHEMBL1735194 0.89 HSPA1A (0.53) HSPA1APABPC1ADORA2AGRM1GRM4
SCHEMBL9241571 0.85 BRD4 (0.56) HSPA1APABPC1ADORA2AGRM1GRM4
SCHEMBL9113912 0.84 PGR (0.46) HSPA1APABPC1ADORA2AGRM1GRM4
SCHEMBL29631855 0.82 GRM1 (0.47) HSPA1APABPC1ADORA2AGRM1GRM4
SCHEMBL1735119 0.77 MEN1 (0.58) HSPA1APABPC1ADORA2AGRM1GRM4
SCHEMBL9812635 0.76 DPP4 (0.68) GRM1GRM4ALPL
SCHEMBL9279014 0.76 DDB1 (0.44) GRM1GRM4MEN1KMT2AALPL
SCHEMBL19834886 0.75 DPP4 (0.55) ADORA2AGRM1GRM4ALPL
SCHEMBL9812593 0.75 DPP4 (0.69) GRM1GRM4ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2162457-B1 CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES BOE TECHNOLOGY GROUP CO LTD (CN) 2018-08-22 EP disclosed
US-8729214-B2 Mixtures resulting from methods for purification of polyether polymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-20 US disclosed
US-20130143992-A1 MIXTURES RESULTING FROM METHODS FOR PURIFICATION OF POLYETHER POLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-06-06 US disclosed
US-8372941-B2 Method for purification of polyether polymers and mixtures resulting therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-02-12 US disclosed
EP-2231749-B1 METHOD FOR PURIFICATION OF POLYETHER POLYMERS SABIC INNOVATIVE PLASTICS IP (NL) 2012-08-01 EP disclosed
EP-2102160-B1 CARBAZOLYL MONOMERS AND POLYMERS GEN ELECTRIC (US) 2011-11-16 EP disclosed
US-20110262920-A1 METHODS FOR PREDICTING SURVIVAL IN CANCER PATIENTS CITY OF HOPE 2011-10-27 US disclosed
EP-2102159-B1 BIS-CARBAZOLE MONOMERS AND POLYMERS GEN ELECTRIC (US) 2011-06-22 EP disclosed
US-7851579-B2 Monomers comprising carbazole units and polymers, dendrimers, and hyper-branched materials derived therefrom; OLEDs having device quantum efficiencies, while still maintaining the potential for the molecules to host red, green, and blue emissive complexes GENERAL ELECTRIC COMPANY (US) 2010-12-14 US disclosed
EP-2231749-A1 METHOD FOR PURIFICATION OF POLYETHER POLYMERS AND MIXTURES RESULTING THEREFROM SABIC Innovative Plastics IP B.V. (NL) 2010-09-29 EP disclosed
EP-1660543-A1 PROCESS FOR FRACTIONATION/CONCENTRATION TO REDUCE THE POLYDISPERSIVITY OF POLYMERS GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP disclosed
US-6906168-B2 Process for fractionation/concentration to reduce the polydispersivity of polymers GENERAL ELECTRIC COMPANY (US) 2005-06-14 US disclosed
WO-2005021599-A1 PROCESS FOR FRACTIONATION/CONCENTRATION TO REDUCE THE POLYDISPERSIVITY OF POLYMERS GENERAL ELECTRIC COMPANY (US) 2005-03-10 WO disclosed
US-20050049392-A1 Process for fractionation/concentration to reduce the polydispersivity of polymers SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-03-03 US disclosed
US-6790934-B2 VIA CATALYTIC POLYMERIZATION IN PRESENCE OF WATER-IMMISCIBLE SOLVENT; EXTRACTION; FILTRATION GENERAL ELECTRIC COMPANY 2004-09-14 US disclosed
EP-1233997-B1 METHOD FOR PURIFICATION OF AROMATIC POLYETHERS GEN ELECTRIC (US) 2003-09-03 EP disclosed
US-20020151675-A1 Method for purification of aromatic polyethers SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-10-17 US disclosed
EP-1233997-A1 METHOD FOR PURIFICATION OF AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2002-08-28 EP disclosed
US-6265521-B1 USING ALKALI METAL SALT OF A DIHYDROXY-SUBSTITUTED AROMATIC HYDROCARBON GENERAL ELECTRIC COMPANY 2001-07-24 US disclosed
WO-2001021686-A1 METHOD FOR PURIFICATION OF AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2001-03-29 WO disclosed