Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968424 | 0.82 | MTNR1A (0.54) | MAPTKMT2AMEN1GAAACACB | |
| SCHEMBL4958520 | 0.82 | TACR1 (0.50) | RECQLTACR1ACACBALDH1A1CASP3 | |
| SCHEMBL4320299 | 0.82 | KDM4E (0.67) | RECQLMAPTKMT2AMEN1TDP1 | |
| SCHEMBL30511512 | 0.82 | KDM4E (0.67) | RECQLMAPTKMT2AMEN1TDP1 | |
| SCHEMBL28536811 | 0.82 | KDM4E (0.67) | RECQLMAPTKMT2AMEN1TDP1 | |
| SCHEMBL31322986 | 0.80 | ELANE (0.57) | RECQLMAPTKMT2AMEN1TDP1 | |
| SCHEMBL11996303 | 0.80 | ELANE (0.57) | RECQLMAPTKMT2AMEN1TDP1 | |
| Formaldehyde SCHEMBL28231874 | 0.80 | MTNR1A (0.51) | MAPTKMT2AMEN1GAAACACB | |
| Acetone SCHEMBL15224657 | 0.80 | KMT2A (0.51) | RECQLMAPTKMT2AMEN1TDP1 | |
| SCHEMBL18256 | 0.79 | KMT2A (0.54) | RECQLMAPTKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187579-B1 | MUTANT CARBOXYPEPTIDASE HAVING A MODIFIED S1 SUBSITE; FOR EFFICIENT TRANSACYLATION OF A PRESELECTED PEPTIDE SUBSTRATE WITH A PRESELECTED NUCLEOPHILE | CARLSBERG A/S (DK) | 2001-02-13 | — | — | US | disclosed |
| US-5945329-A | MUTANT CARBOXYPEPTIDASE Y WITH MODIFIED ACTIVE SITES ABLE TO CATALYZE TRANACYLATION OF PRESELECTED PEPTIDE SUBSTRATE WITH PRESELECTED NUCLEOPHILE; FOR POST-TRANSLATIONAL MODIFICATION OF RECOMBINANT PEPTIDES | CARLSBERG A/S (DK) | 1999-08-31 | — | — | US | disclosed |