Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.50 |
| ▸ | HTR3B | O95264 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327982 | 1.00 | ALDH1A1 (0.51) | ALDH1A1TAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL4340460 | 0.84 | HTR3E (0.56) | ALDH1A1TAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL4322049 | 0.84 | HTR3E (0.56) | ALDH1A1TAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL30572312 | 0.80 | HTR3E (0.59) | ALDH1A1TAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL2473717 | 0.80 | HTR3E (0.59) | ALDH1A1TAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL657202 | 0.79 | PDPK1 (0.72) | ALDH1A1TAAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL657203 | 0.79 | PDPK1 (0.72) | ALDH1A1TAAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL657201 | 0.79 | PDPK1 (0.72) | ALDH1A1TAAR1PLAAT3PLAAT5PLAAT2 | |
| Hydrochloric Acid SCHEMBL31606746 | 0.79 | HTR3E (0.57) | ALDH1A1TAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL80581 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TAAR1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146696-A1 | USE OF INDOLE-3-CARBOXYLIC ESTERS FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE | Universität Tübingen (DE) | 2009-12-10 | — | — | WO | disclosed |