SCHEMBL80581

SCHEMBL80581

O=C(O)CCc1cccc(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
KMT2A Q03164 2/20 0.67
THRA P10827 1/20 0.64
THRB P10828 1/20 0.64
FFAR1 O14842 3/20 0.63
FFAR4 Q5NUL3 1/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
KEAP1 Q14145 1/20 0.61
PLAAT3 P53816 2/20 0.59
PLAAT5 Q96KN8 2/20 0.59
PLAAT2 Q9NWW9 2/20 0.59
PLAAT4 Q9UL19 2/20 0.59
PTPRB P23467 1/20 0.57
CDC25A P30304 1/20 0.57
CDC25B P30305 1/20 0.57
PTEN P60484 1/20 0.57
PTPMT1 Q8WUK0 1/20 0.57
PPARG P37231 1/20 0.56
MEN1 O00255 1/20 0.55
HPGD P15428 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5024832 0.89 SMN1; SMN2 (0.68) ALDH1A1KMT2ATHRATHRBFFAR1
SCHEMBL7829175 0.87 SMN1; SMN2 (0.67) ALDH1A1KMT2ATHRATHRBFFAR1
SCHEMBL7332799 0.86 TAAR1 (0.57) ALDH1A1KMT2AFFAR1FFAR4SMN1; SMN2
SCHEMBL7511993 0.86 ALDH1A1 (0.60) ALDH1A1KMT2ATHRATHRBFFAR1
SCHEMBL18126611 0.86 MAPT (0.66) ALDH1A1KMT2ASMN1; SMN2PLAAT3PLAAT5
SCHEMBL70271 0.86 KEAP1 (0.74) FFAR1FFAR4SMN1; SMN2KEAP1PTPRB
SCHEMBL3252805 0.85 PLAAT3 (0.55) ALDH1A1KMT2ATHRATHRBFFAR1
Phenyl Propionic Acid SCHEMBL28551997 0.84 FFAR1 (0.56) ALDH1A1KMT2ATHRATHRBFFAR1
Hydrochloric Acid SCHEMBL10982620 0.84 KEAP1 (0.71) FFAR1FFAR4SMN1; SMN2KEAP1PTPRB
SCHEMBL1180332 0.83 ALDH1A1 (0.57) ALDH1A1KMT2ATHRATHRBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-111116507-A Synthetic process of indoxacarb 江苏腾龙生物药业有限公司 2020-05-08 CN claimed
EP-1354906-B1 Polyamide resin MITSUBISHI GAS CHEMICAL CO (JP) 2012-12-05 EP claimed
EP-2004789-B1 A STABILIZED LIQUID ENZYME COMPOSITION NOVOZYMES AS (DK) 2012-08-29 EP claimed
EP-2383330-A1 A stabilized liquid enzyme composition Novozymes A/S (DK) 2011-11-02 EP claimed
EP-2004789-A1 A STABILIZED LIQUID ENZYME COMPOSITION Novozymes A/S (DK) 2008-12-24 EP claimed
WO-2007113241-A1 A STABILIZED LIQUID ENZYME COMPOSITION NOVOZYMES A/S (DK) 2007-10-11 WO claimed
US-20070232514-A1 STABILIZED LIQUID ENZYME COMPOSITION NOVOZYMES A/S (DK) 2007-10-04 US claimed
US-6841651-B2 Polyamide resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-01-11 US claimed
EP-1282680-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2003-02-12 EP claimed
US-6503413-B2 Polyalkylene polysiloxane, buffering agent, aqueous carrier THE PROCTER & GAMBLE COMPANY 2003-01-07 US claimed
EP-1255806-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2002-11-13 EP claimed
US-20020011584-A1 Stable, aqueous compositions for treating surfaces, especially fabrics THE PROCTOR & GAMBLE COMPANY 2002-01-31 US claimed
US-20020010154-A1 Compositions comprising cyclodextrin THE PROCTER & GAMBLE COMPANY 2002-01-24 US claimed
WO-2001088076-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2001-11-22 WO claimed
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 US claimed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 WO claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010154-A1 Compositions comprising cyclodextrin FFAR4, FRG1, FGB ALDH1A1 3053/4885KMT2A 4191/4885THRA 3847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.