Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742233 | 0.86 | KDM4E (0.60) | KDM4ELMNASMN1; SMN2MAPK10ALOX12 | |
| SCHEMBL2605820 | 0.84 | KMT2A (0.56) | KDM4ELMNASMN1; SMN2MAPK10ALOX12 | |
| SCHEMBL14543978 | 0.83 | SMN1; SMN2 (0.59) | KDM4ELMNASMN1; SMN2MAPK10ALOX12 | |
| SCHEMBL7131019 | 0.81 | KMT2A (0.58) | KDM4ELMNASMN1; SMN2MAPK10ALOX12 | |
| SCHEMBL10744953 | 0.81 | ALDH1A1 (0.56) | KDM4ELMNASMN1; SMN2MAPK10ALOX12 | |
| SCHEMBL7046945 | 0.81 | PTGS2 (0.57) | KDM4ELMNASMN1; SMN2MAPK10ALOX12 | |
| SCHEMBL2403269 | 0.81 | KMT2A (0.71) | KDM4ELMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL21101917 | 0.80 | KDM4E (0.55) | KDM4ELMNASMN1; SMN2MAPK10ALOX12 | |
| SCHEMBL4965033 | 0.79 | PTGS2 (0.55) | KDM4ELMNASMN1; SMN2MAPK10ALOX12 | |
| SCHEMBL499116 | 0.79 | GAA (0.61) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |
| US-20070243255-A1 | Multifunctional supramolecular hydrogels as biomaterials | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2007-10-18 | — | — | US | disclosed |
| WO-2006067224-A2 | SPIRO-BENZODIOXOLE AND SPIRO-BENZODIOXANE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | BIOVITRUM AB (PUBL) (SE) | 2006-06-29 | — | — | WO | disclosed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-4851526-A | ANTIARRYTHMIA, HYPOTENSIVE, ANTIISCHEMIC | SCHERING A.G. (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0306440-A2 | 1-(4-substituted phenyl)-1H-imidazoles as cardiovascular agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | disclosed |