SCHEMBL432102

SCHEMBL432102

C=C(C)C(=O)NC(C)(C)CCC(=O)c1ncc[nH]1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
KMT2A Q03164 1/20 0.33
FDPS P14324 1/20 0.31
BRAF P15056 1/20 0.31
HDAC1 Q13547 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432450 0.83 ALDH1A1 (0.42) NPC1RAB9AKMT2A
SCHEMBL1142559 0.79 TBXAS1 (0.43) FDPS
SCHEMBL6321087 0.79 NPC1 (0.37) NPC1RAB9AKMT2ABRAFHDAC1
SCHEMBL6314740 0.76 NPC1 (0.35) NPC1RAB9AKMT2AHDAC1
SCHEMBL10482284 0.71 THRB (0.39) NPC1RAB9AKMT2ABRAFHDAC1
SCHEMBL1237700 0.70 NPC1 (0.43) NPC1RAB9AKMT2AFDPSBRAF
SCHEMBL19881205 0.70 ALDH1A1 (0.37)
SCHEMBL1147584 0.70 NPC1 (0.41) NPC1RAB9AKMT2AFDPSBRAF
SCHEMBL5052589 0.69 NAALAD2 (0.44) KMT2AHDAC1
SCHEMBL7574578 0.69 NPC1 (0.46) NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582684-B2 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-01 US claimed
US-20250367610-A1 Block Copolymers Grafted to Porous Polymeric Substrate SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-12-04 US disclosed
EP-4543575-A1 BLOCK COPOLYMERS GRAFTED TO POROUS POLYMERIC SUBSTRATE Solventum Intellectual Properties Company (US) 2025-04-30 EP disclosed
EP-2588219-B1 FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY NEOGEN FOOD SAFETY US HOLDCO CORP (US) 2024-05-29 EP disclosed
WO-2023248020-A1 BLOCK COPOLYMERS GRAFTED TO POROUS POLYMERIC SUBSTRATE 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-28 WO disclosed
EP-2376689-B1 FUNCTIONALIZED NONWOVEN ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2023-09-13 EP disclosed
US-11279731-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-03-22 US disclosed
EP-3326711-B1 GRAFT COPOLYMER FUNCTIONALIZED ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-07-07 EP disclosed
US-10988827-B2 Coalescing elements in copper production 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-04-27 US disclosed
EP-3255085-B1 LIGAND GRAFT FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES CO (US) 2020-06-10 EP disclosed
WO-2009148869-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-10 WO disclosed
US-7582684-B2 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-01 US disclosed
US-7553417-B2 Functionalized substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-06-30 US disclosed
US-20090098359-A1 HYDROPHILIC POROUS SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY 2009-04-16 US disclosed
US-20070154703-A1 FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY 2007-07-05 US disclosed
US-20070154651-A1 METHOD OF MAKING FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY 2007-07-05 US disclosed
US-20070142590-A1 Method of making macroporous anion exchange resins 3M INNOVATIVE PROPERTIES COMPANY 2007-06-21 US disclosed
US-7098253-B2 particles of hydrophilic, crosslinked copolymers of N,N'-alkylenebis(meth)acrylamide and a sulfonated N,N'-alkylene bisacrylic amide; chromatographic columns, composite materials, filters; large furface area, ease of manufacture, low material cost, variety of fiber texture, densities 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-08-29 US disclosed
US-20050261384-A1 MACROPOROUS ION EXCHANGE RESINS 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed
US-20050261385-A1 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279731-B2 Ligand functional substrates PCNA, POLM, POLL NPC1 4692/4885RAB9A 3934/4885KMT2A 3710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.