Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4324204 | 0.85 | ATP4A (0.55) | RAB9AMAPTNPC1GFER | |
| SCHEMBL4324209 | 0.83 | RAB9A (0.44) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL4326106 | 0.83 | NPC1 (0.63) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL4333577 | 0.80 | MAPT (0.53) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL4328007 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL366845 | 0.77 | RAB9A (0.54) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL4330172 | 0.76 | MAPT (0.55) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL475998 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL9373472 | 0.74 | RAB9A (0.64) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL1553078 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |