Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076053 | 0.80 | KEAP1 (0.54) | MAPTMTNR1AMTNR1BKEAP1NFE2L2 | |
| SCHEMBL4323833 | 0.77 | KEAP1 (0.63) | MAPTMTNR1AMTNR1BKEAP1NFE2L2 | |
| SCHEMBL6076677 | 0.76 | MTNR1A (0.72) | MAPTMTNR1AMTNR1BKEAP1NFE2L2 | |
| SCHEMBL6078133 | 0.75 | LMNA (0.55) | MAPTSNCAMTNR1AKEAP1NFE2L2 | |
| SCHEMBL3211644 | 0.75 | KMT2A (0.54) | CNR1GRM5P2RX7KDM4EMEN1 | |
| SCHEMBL6076266 | 0.74 | KEAP1 (0.56) | MAPTMTNR1AMTNR1BKEAP1NFE2L2 | |
| SCHEMBL6075758 | 0.74 | MTNR1A (0.56) | MAPTMTNR1AMTNR1BKEAP1NFE2L2 | |
| SCHEMBL6075719 | 0.73 | MAPT (0.57) | MAPTKEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL6075722 | 0.73 | MAPT (0.57) | MAPTKEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL16760266 | 0.73 | KMT2A (0.48) | MAPTCNR1P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054235-A1 | Benzoheterocyclylethylbenzamide derivatives | BAYER CROPSCIENCE AG (DE) | 2009-02-26 | — | — | US | disclosed |
| CN-101223136-A | New benzoheterocyclylethylbenzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2008-07-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054235-A1 | Benzoheterocyclylethylbenzamide derivatives | CYP51A1, CBR3, ERG28 | MAPT 3550/4885SNCA 3270/4885MTNR1A 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.