Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431472 | 0.90 | CDC25A (0.39) | LMNAKIF11ALDH1A1KDM4ETDP1 | |
| SCHEMBL431474 | 0.77 | CYP2C19 (0.38) | KIF11 | |
| SCHEMBL432334 | 0.77 | CYP2C19 (0.38) | KIF11 | |
| SCHEMBL13469291 | 0.70 | KIF11 (0.48) | LMNAKIF11ALDH1A1MEN1RAB9A | |
| SCHEMBL19454902 | 0.69 | CNR1 (0.54) | LMNAALDH1A1KDM4EPTPRCPTPN13 | |
| SCHEMBL10315011 | 0.69 | KIF11 (0.49) | LMNAKIF11ALDH1A1MEN1RAB9A | |
| SCHEMBL10387238 | 0.67 | CNR1 (0.55) | LMNAALDH1A1KDM4EPTPRCKMT2A | |
| SCHEMBL4545013 | 0.65 | CNR1 (0.50) | LMNAALDH1A1KDM4ECA12CA7 | |
| SCHEMBL13523659 | 0.65 | KIF11 (0.51) | KIF11 | |
| SCHEMBL431461 | 0.65 | KIF11 (0.46) | KIF11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | KIT, ABCG2, TK1 | LMNA 3375/4885KIF11 2671/4885ALDH1A1 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.