Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.36 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432329 | 0.90 | LMNA (0.42) | ALDH1A1LMNAKIF11KDM4ETDP1 | |
| SCHEMBL432334 | 0.82 | CYP2C19 (0.38) | KIF11HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL431474 | 0.82 | CYP2C19 (0.38) | KIF11HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL8884895 | 0.71 | ALDH1A1 (0.48) | CDC25ACDC25BALDH1A1TBXA2RHTR2C | |
| SCHEMBL431461 | 0.68 | KIF11 (0.46) | KIF11MAPT | |
| SCHEMBL12926371 | 0.68 | MEN1 (0.47) | ALDH1A1ADRA1AMAPK1KIF11HDAC1 | |
| SCHEMBL18160139 | 0.67 | KIF11 (0.45) | CYP1A2KIF11HDAC1MAPTHDAC3 | |
| SCHEMBL3022513 | 0.67 | LMNA (0.49) | ALDH1A1TBXA2RLMNAMAPK1HDAC1 | |
| SCHEMBL3034455 | 0.67 | LMNA (0.49) | ALDH1A1TBXA2RLMNAMAPK1HDAC1 | |
| SCHEMBL34262 | 0.66 | KIF11 (0.50) | ALDH1A1SLC6A3ADRA1AMAPK1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | KIT, ABCG2, TK1 | CDC25A 4513/4885CDC25B 4553/4885ALDH1A1 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.