Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | CEL | P19835 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3793544 | 0.95 | CHRNB2 (0.57) | CHRNB2CHRNA4TAAR1PTGDR2PTGDR | |
| SCHEMBL3795015 | 0.93 | CHRNB2 (0.55) | CHRNB2CHRNA4TAAR1PTGDR2PTGDR | |
| SCHEMBL3781719 | 0.91 | CHRNB2 (0.61) | CHRNB2CHRNA4TAAR1PTGDR2PTGDR | |
| SCHEMBL432356 | 0.84 | GAA (0.53) | CHRNB2CHRNA4PTGDR2PTGDRPTGER2 | |
| SCHEMBL2469041 | 0.82 | CHRNB2 (0.68) | CHRNB2CHRNA4TAAR1TMEM97SIGMAR1 | |
| SCHEMBL3781247 | 0.81 | NOS3 (0.47) | CHRNB2CHRNA4TAAR1PTGDR2PTGDR | |
| SCHEMBL3781338 | 0.81 | TSHR (0.46) | CHRNB2CHRNA4TAAR1PTGDR2PTGDR | |
| SCHEMBL434518 | 0.81 | OPRL1 (0.56) | CHRNB2CHRNA4PTGDR2PTGDRPTGER2 | |
| SCHEMBL432639 | 0.80 | GAA (0.58) | PTGDR2PTGDRPTGER2GAATSHR | |
| SCHEMBL15566598 | 0.80 | PTGDR2 (0.49) | CHRNB2CHRNA4PTGDR2PTGDRPTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CHRNB2 3205/4885CHRNA4 4337/4885TAAR1 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.