Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331800 | 0.88 | SCN9A (0.40) | SCN9ACNR1CNR2EGFRL3MBTL1 | |
| SCHEMBL13578024 | 0.86 | CPT2 (0.47) | MEN1KMT2AALDH1A1CPT2CPT1A | |
| SCHEMBL13577917 | 0.85 | RXFP1 (0.42) | SCN9ACNR1CNR2L3MBTL1F2RL3 | |
| SCHEMBL13578018 | 0.85 | CPT2 (0.46) | SCN9ATSHRF2RL3MEN1KMT2A | |
| SCHEMBL13577941 | 0.84 | ASH1L (0.48) | SCN9ACNR2EGFRL3MBTL1F2RL3 | |
| SCHEMBL4326615 | 0.84 | SCN9A (0.49) | SCN9ACNR2EGFRL3MBTL1F2RL3 | |
| SCHEMBL4333426 | 0.84 | ALDH1A1 (0.48) | SCN9AEGFRL3MBTL1F2RL3MEN1 | |
| Hydrochloric Acid SCHEMBL4326712 | 0.84 | ASH1L (0.47) | SCN9ACNR2EGFRL3MBTL1F2RL3 | |
| SCHEMBL4324605 | 0.84 | KDM4E (0.42) | CNR1CNR2L3MBTL1TSHRKMT2A | |
| SCHEMBL13577916 | 0.84 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |