Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330806 | 0.89 | CAMK2D (0.45) | ALDH1A1HPGDTDP1SCN9AMEN1 | |
| SCHEMBL4453609 | 0.87 | F2RL3 (0.43) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL13577950 | 0.86 | MAPK1 (0.45) | ALDH1A1GAASMN1; SMN2SCN9AMEN1 | |
| SCHEMBL13577954 | 0.85 | DRD2 (0.45) | ALDH1A1HPGDTDP1SCN9AMEN1 | |
| SCHEMBL13577941 | 0.85 | ASH1L (0.48) | ALDH1A1HPGDTDP1SCN9AMEN1 | |
| SCHEMBL4326615 | 0.85 | SCN9A (0.49) | ALDH1A1KDM4EHPGDGAATDP1 | |
| Hydrochloric Acid SCHEMBL4326712 | 0.84 | ASH1L (0.47) | ALDH1A1HPGDTDP1SCN9AMEN1 | |
| SCHEMBL4324539 | 0.84 | SCN9A (0.44) | ALDH1A1HPGDTDP1SCN9AMEN1 | |
| SCHEMBL13577956 | 0.83 | LMNA (0.47) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4335986 | 0.81 | NPC1 (0.47) | HPGDSMN1; SMN2SCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |