Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17917509 | 0.88 | KMT2A (0.54) | MAOAALDH1A1MAPTLMNACSNK2A2 | |
| SCHEMBL4324926 | 0.82 | MAOA (0.60) | MAOAALDH1A1KDM4EMAPTGLA | |
| SCHEMBL9182503 | 0.82 | CYP19A1 (0.56) | MAOAALDH1A1KDM4EMAPTGLA | |
| SCHEMBL11151056 | 0.82 | PTGS2 (0.64) | MAOAALDH1A1KDM4EMAPTGLA | |
| SCHEMBL25379884 | 0.78 | CSNK2A2 (0.77) | MAOAMAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL10502060 | 0.78 | CYP19A1 (0.55) | MAOAALDH1A1KDM4EMAPTGLA | |
| SCHEMBL3364130 | 0.77 | GPR35 (0.52) | MAOAALDH1A1MAPTLMNAGPR35 | |
| SCHEMBL29506802 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAMEN1GAA | |
| SCHEMBL782755 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAMEN1GAA | |
| SCHEMBL31116911 | 0.76 | MAPT (0.56) | MAOAALDH1A1KDM4EMAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5176854-A | Xanthone Derivatives | HITACHI, LTD. (JP) | 1993-01-05 | — | — | US | claimed |
| US-20230037858-A1 | COMPOSITION CONTAINING ADDITION CONDENSATION PRODUCT, METHOD FOR PRODUCING SAME, USE OF SAME, POLYMERIZATION VESSEL, AND METHOD FOR PRODUCING POLYMER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-02-09 | — | — | US | disclosed |
| US-11345651-B2 | Addition condensation product, production method and use of same, polymerization vessel, and production method of polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-05-31 | — | — | US | disclosed |
| US-20210403405-A1 | ADDITION CONDENSATION PRODUCT, PRODUCTION METHOD AND USE OF SAME, POLYMERIZATION VESSEL, AND PRODUCTION METHOD OF POLYMER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
| US-20210403611-A1 | PRODUCTION METHOD OF ADDITION CONDENSATION PRODUCT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
| EP-1896467-B1 | TRICYCLIC OPIOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-01 | — | — | EP | disclosed |
| US-20090275610-A1 | TRICYCLIC OPIOID MODULATORS | DECORTE BART | 2009-11-05 | — | — | US | disclosed |
| US-20090275610-A1 | TRICYCLIC OPIOID MODULATORS | DECORTE BART | 2009-11-05 | — | — | US | disclosed |
| US-20090275610-A1 | TRICYCLIC OPIOID MODULATORS | DECORTE BART | 2009-11-05 | — | — | US | disclosed |
| US-7582650-B2 | Tricyclic opioid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-01 | — | — | US | disclosed |
| CN-85107531-A | Process for producing vinyl chloride polymer | — | 1987-01-21 | — | — | CN | disclosed |
| US-4574114-A | Photosensitive composition for electrophotography having polyvinyl carbazole and silicone oil | MITA INDUSTRIAL COMPANY, LTD. (JP) | 1986-03-04 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
| US-4521504-A | DICHROMATIC IMAGES-CONDUCTIVE SUBSTRATE LAMINATED WITH PHOTOCONDUCTIVE | RICOH COMPANY, LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| US-4469769-A | Photosensitive material for electrophotography contains halo-benzoquinone sensitizer | MITA INDUSTRIAL CO. LTD. (JP) | 1984-09-04 | — | — | US | disclosed |
| EP-0114482-A2 | A photosensitive composition for electrophotography | MITA INDUSTRIAL CO. LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |
| EP-0100581-A2 | Photosensitive material for electrophotography | MITA INDUSTRIAL CO. LTD. (JP) | 1984-02-15 | — | — | EP | disclosed |
| US-4370398-A | Electrostatic copying process | RICOH COMPANY, LTD. (JP) | 1983-01-25 | — | — | US | disclosed |
| US-4361638-A | AMORPHOUS SILICON AND CARBON BASE MATERIAL DOPED WITH HYDROGEN AND FLUORINE | FUJI PHOTO FILM CO., LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| US-4267344-A | 3-PENTA/ALKOXY/BENZYL-; -XANTHYL-, -THIOXANTHYL-, OR -SELENOXANTHYLOXAZOLIDINE-2,5-DIONES | PROTEINKEMISK INSTITUT. TILKNYTTET AKADEMIET FOR DE TEKNISKE VIDENSKABER (DK) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275610-A1 | TRICYCLIC OPIOID MODULATORS | OPRD1, OPRM1, OPRK1 | MAOA 555/4885ALDH1A1 927/4885KDM4E 2206/4885 |
| US-11345651-B2 | Addition condensation product, production method and use of same, polymerization vessel, and production method of polymer | MCCC2, PYCARD, PCCA | MAOA 386/4885ALDH1A1 2590/4885KDM4E 1432/4885 |
| US-20210403405-A1 | ADDITION CONDENSATION PRODUCT, PRODUCTION METHOD AND USE OF SAME, POLYMERIZATION VESSEL, AND PRODUCTION METHOD OF POLYMER | MCCC2, PYCARD, PCCA | MAOA 386/4885ALDH1A1 2590/4885KDM4E 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.