Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4324878 | 0.99 | CRHR1 (0.36) | CRHR1WDR5KMT2ATP53MAPT | |
| SCHEMBL13578902 | 0.74 | WDR5 (0.43) | WDR5KMT2AMAPTEGFRKDR | |
| SCHEMBL13578882 | 0.71 | EGFR (0.42) | WDR5KMT2AMAPTEGFRKDR | |
| SCHEMBL13578880 | 0.70 | KMT2A (0.43) | CRHR1WDR5KMT2AMAPTEGFR | |
| SCHEMBL13578886 | 0.70 | MAPK1 (0.50) | WDR5KMT2ATP53EGFRKDR | |
| SCHEMBL13578892 | 0.69 | PIK3CA (0.54) | KMT2ATP53MAPTEGFRKDR | |
| SCHEMBL13578869 | 0.69 | KDR (0.43) | CRHR1WDR5KMT2AMAPTEGFR | |
| SCHEMBL8032963 | 0.69 | CRHR1 (0.36) | CRHR1WDR5KMT2AEGFRKDR | |
| SCHEMBL5236485 | 0.68 | KDR (0.51) | WDR5KMT2ATP53MAPTEGFR | |
| SCHEMBL4319399 | 0.68 | ALDH1A1 (0.43) | WDR5KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144632-A1 | NOVEL COMPOUNDS | PFIZER LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009144632-A1 | NOVEL COMPOUNDS | PFIZER LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |