Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094653 | 0.72 | WDR5 (0.40) | CRHR1KMT2AWDR5 | |
| SCHEMBL4325142 | 0.69 | CRHR1 (0.36) | CRHR1KMT2AWDR5EGFRKDR | |
| SCHEMBL13578880 | 0.69 | KMT2A (0.43) | CRHR1KMT2AWDR5MEN1EGFR | |
| Hydrochloric Acid SCHEMBL4324878 | 0.69 | CRHR1 (0.36) | CRHR1KMT2AWDR5EGFRKDR | |
| SCHEMBL24274758 | 0.67 | LMNA (0.35) | KMT2ALMNAEGFRPDGFRBLCK | |
| SCHEMBL31115519 | 0.67 | SOS1 (0.50) | — | |
| SCHEMBL5236485 | 0.66 | KDR (0.51) | KMT2AWDR5LMNAMEN1EGFR | |
| SCHEMBL31723401 | 0.66 | EGFR (0.38) | KMT2ALMNAEGFRSMN1; SMN2CXCL8 | |
| SCHEMBL6094657 | 0.66 | NR1I2 (0.36) | KMT2AWDR5LMNAMEN1EGFR | |
| SCHEMBL29931161 | 0.65 | PDE10A (0.40) | KMT2AWDR5LMNAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |