Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328322 | 0.85 | ESR1 (0.48) | CALM1KDM4ETRPV1ESR1ADRA2A | |
| SCHEMBL10316571 | 0.82 | MTOR (0.46) | KDM4EF13A1ESR1EGFRACHE | |
| SCHEMBL1578417 | 0.79 | CALM1 (0.38) | CALM1KDM4EF13A1ESR1ALDH1A1 | |
| SCHEMBL1578114 | 0.78 | KMT2A (0.38) | CALM1KDM4ELMNACYP3A4 | |
| SCHEMBL27498004 | 0.75 | CHRM1 (0.51) | KDM4EALDH1A1CHRM2CHRM5CHRM1 | |
| SCHEMBL4325564 | 0.75 | ESR1 (0.52) | KDM4EF13A1ESR1ADRA2ASLC6A2 | |
| SCHEMBL4753457 | 0.74 | ALOX5 (0.53) | KDM4ETRPV1ESR1ADRA2AADORA3 | |
| SCHEMBL4333170 | 0.72 | PPARA (0.44) | KDM4EALDH1A1ADRB3 | |
| SCHEMBL25337380 | 0.72 | ESR1 (0.45) | KDM4ETRPV1ESR1ADRA2AADORA3 | |
| SCHEMBL946899 | 0.71 | RXRA (0.43) | TRPV1ESR1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |