SCHEMBL538038

SCHEMBL538038

CSCC[C@H](NC(N)=O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
TSHR P16473 2/20 0.52
CA2 P00918 4/20 0.51
CA1 P00915 3/20 0.51
ALDH1A1 P00352 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
FOLH1 Q04609 1/20 0.49
MAPK1 P28482 1/20 0.48
RNPEP Q9H4A4 1/20 0.47
FNTA P49354 2/20 0.47
FNTB P49356 2/20 0.47
PGGT1B P53609 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538037 1.00 LMNA (0.54) LMNATSHRCA2CA1ALDH1A1
SCHEMBL3282392 1.00 LMNA (0.54) LMNATSHRCA2CA1ALDH1A1
SCHEMBL538339 0.86 TSHR (0.54) LMNATSHRCA2CA1ALDH1A1
SCHEMBL538340 0.86 TSHR (0.54) LMNATSHRCA2CA1ALDH1A1
SCHEMBL14754318 0.85 TSHR (0.50) LMNATSHRCA2CA1ALDH1A1
SCHEMBL4326342 0.84 LMNA (0.57) LMNATSHRCA2CA1ALDH1A1
SCHEMBL26090455 0.84 LMNA (0.66) LMNACA2ALDH1A1NPSR1FOLH1
SCHEMBL1298472 0.84 LMNA (0.57) LMNATSHRCA2CA1ALDH1A1
SCHEMBL27896443 0.83 FNTA (0.50) LMNATSHRCA2CA1ALDH1A1
SCHEMBL109681 0.82 LMNA (0.55) LMNACA2CA1ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116374974-A Recycling method of methionine crude product crystallization mother liquor in methionine potassium salt process 天宝动物营养科技股份有限公司 2023-07-04 CN claimed
US-6953677-B2 Recombinant L-N-carbamoylase from Arthrobacter aurescens and method of producing L-amino acids therewith DEGUSSA AG (DE) 2005-10-11 US claimed
EP-1209234-A1 STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2002-05-29 EP claimed
EP-0628637-B1 PROCESS FOR PRODUCING D-ALPHA-AMINO ACIDS KANEGAFUCHI CHEMICAL IND (JP) 2001-06-13 EP claimed
US-5902736-A USING DECARBAMYLASE FROM COMAMONAS, ALCALIGENES, RHIZOBIUM, BLASTOBACTER, SPOROSARCINA, AND BRADYRHYZOBIUM SPECIES IN AQUEOUS MEDIUM; AS CHEMICAL INTERMEDIATES FOR SEMISYNTHETIC PENICILLIN AND CEPHALOSPORIN KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1999-05-11 US claimed
EP-0628637-A1 PROCESS FOR PRODUCING D-$g(a)-AMINO ACID Kanegafuchi Chemical Industry Co., Ltd. (JP) 1994-12-14 EP claimed
US-4148688-A Process for preparing L-methionine KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1979-04-10 US claimed
JP-62275696-A None JP disclosed
JP-52125692-A None JP disclosed
JP-63218655-A None JP disclosed
CN-115772513-B D-carbamyl hydrolase mutant, gene, expression vector and application thereof 江南大学 2025-05-02 CN disclosed
EP-4299581-A1 METHOD FOR THE PREPARATION OF DL-METHIONINE AND DIASTEREOMERICALLY PURE PREPARATIO OF DLLD METHIONYLMETHIONINE Evonik Operations GmbH (DE) 2024-01-03 EP disclosed
CN-116855481-A Nitrilase mutant and application thereof in preparation of 2-amino-4-methylthiobutyric acid 浙江工业大学 2023-10-10 CN disclosed
EP-0159866-A2 Process for production of L-amino acids DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-10-30 EP disclosed
US-4423175-A AND ALKALINE EARTH, ZINC, OR TIN COMPOUND AJINOMOTO COMPANY INCORPORATED (JP) 1983-12-27 US disclosed
US-4384059-A ADDITIONALLY WITH ALKALINE EARTH METAL, ZINC AND ORGANO TIN COMPOUNDS AJINOMOTO COMPANY INCORPORATED (JP) 1983-05-17 US disclosed
US-4237227-A ENZYMATIC HYDROLYSIS OF A HYDANTOIN KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1980-12-02 US disclosed
US-4148688-A Process for preparing L-methionine KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1979-04-10 US disclosed
US-4148688-A Process for preparing L-methionine KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1979-04-10 US disclosed
JP-S52125692-A PREPARATION OF L-METHIONINE KANEGAFUCHI CHEM IND CO LTD 1977-10-21 JP disclosed