Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326342 | 0.86 | LMNA (0.57) | ALDH1A1NPSR1LMNARNPEPPOLB | |
| SCHEMBL13603010 | 0.86 | ALDH1A1 (0.43) | ALDH1A1NPSR1LMNARNPEPMEN1 | |
| SCHEMBL1298472 | 0.86 | LMNA (0.57) | ALDH1A1NPSR1LMNARNPEPPOLB | |
| SCHEMBL12018961 | 0.86 | ALDH1A1 (0.43) | ALDH1A1NPSR1LMNARNPEPMEN1 | |
| SCHEMBL12562326 | 0.86 | ALDH1A1 (0.43) | ALDH1A1NPSR1LMNARNPEPMEN1 | |
| SCHEMBL28257478 | 0.84 | LMNA (0.55) | ALDH1A1NPSR1LMNARNPEPPOLB | |
| SCHEMBL9972470 | 0.81 | CTSS (0.44) | ALDH1A1LMNAKMT2ACTSSCTSK | |
| SCHEMBL5990092 | 0.81 | CTSS (0.44) | ALDH1A1LMNAKMT2ACTSSCTSK | |
| SCHEMBL3265338 | 0.81 | CTSS (0.44) | ALDH1A1LMNAKMT2ACTSSCTSK | |
| SCHEMBL23753625 | 0.81 | CTSS (0.44) | ALDH1A1NPSR1LMNARNPEPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287402-A1 | Cathepsin inhibitors | MERCK FROSST CANADA & CO. (CA) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287402-A1 | Cathepsin inhibitors | CTSB, CTSK, CTSS | ALDH1A1 2983/4885NPSR1 257/4885LMNA 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.