Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953991 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL9593585 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL432727 | 0.80 | MAOB (0.41) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL9593484 | 0.78 | THRB (0.46) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL8760668 | 0.78 | MEN1 (0.63) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL1144066 | 0.78 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29712843 | 0.78 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8091206 | 0.78 | POLB (0.49) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL28282844 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL18484513 | 0.75 | GABRA1 (0.50) | MEN1KMT2AGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |