SCHEMBL4327593

SCHEMBL4327593

C=CC(=O)NCCc1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MPO P05164 7/20 0.50
SLC6A4 P31645 1/20 0.44
TGM2 P21980 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
AKR1B1 P15121 1/20 0.43
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42
ALDH1A1 P00352 2/20 0.41
SLC6A5 Q9Y345 1/20 0.41
NQO2 P16083 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410698 0.83 TSHR (0.52) MPOSLC6A4TGM2AKR1B1CA12
SCHEMBL9482489 0.82 KMT2A (0.48) TGM2TAAR1ALDH1A1HPGDSMN1; SMN2
SCHEMBL3176740 0.82 HIF1A (0.56) TAAR1ALDH1A1HPGDSMN1; SMN2
SCHEMBL27640734 0.81 NQO2 (0.61) MPOSLC6A4TAAR1AKR1B1NQO2
SCHEMBL68672 0.80 MTNR1A (0.66) TGM2CA12CA2NQO2
SCHEMBL5309632 0.79 MPO (0.56) MPOSLC6A4TAAR1AKR1B1CA12
SCHEMBL8477022 0.78 MTNR1A (0.68) TGM2TAAR1CA12CA2ALDH1A1
Catechol SCHEMBL28144792 0.78 ZDHHC20 (0.51) TGM2ALDH1A1SMN1; SMN2GAA
SCHEMBL1039416 0.77 MTNR1A (0.63) MPOALDH1A1NQO2HPGD
SCHEMBL17307602 0.77 MPO (0.55) MPOSLC6A4TAAR1AKR1B1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090288855-A1 POSITIVE-TYPE RADIATION-SENSITIVE RESIN COMPOSITION FOR PRODUCING A METAL-PLATING FORMED MATERIAL, TRANSCRIPTION FILM AND PRODUCTION METHOD OF A METAL-PLATING FORMED MATERIAL JSR CORPORATION (JP) 2009-11-26 US disclosed
US-7304117-B2 Reactive yellow dyes useful for ocular devices BAUSCH & LOMB INCORPORATED (US) 2007-12-04 US disclosed
US-7241312-B2 Silicone intraocular lens with blue light absorption properties BAUSCH & LOMB INCORPORATED (US) 2007-07-10 US disclosed
US-20070031758-A1 Positive-type radiation-sensitive resin composition for producing a metal-plating formed material, transcription film and production method of a metal-plating formed material JSR CORPORATION (JP) 2007-02-08 US disclosed
EP-1750176-A2 Positive-type radiation-sensitive resin composition for producing a metal-plating formed material, transcription film and production method of a metal-plating formed material JSR Corporation (JP) 2007-02-07 EP disclosed
US-20060241263-A1 Novel reactive yellow dyes useful for ocular devices LAI YU-CHIN 2006-10-26 US disclosed
US-20060241264-A1 Novel reactive yellow dyes useful for ocular devices SALIX PHARMACEUTICALS, LTD. 2006-10-26 US disclosed
CN-1849375-A Novel reactive yellow dyes for ophthalmic devices BAUSCH & LOMB (US) 2006-10-18 CN disclosed
US-7098283-B2 Reactive yellow dyes useful for ocular devices BAUSCH & LOMB INCORPORATED (US) 2006-08-29 US disclosed
EP-1663334-A1 INTRAOCULAR LENS WITH BLUE LIGHT ABSORPTION PROPERTIES AND PROCESS BAUSCH & LOMB INCORPORATED (US) 2006-06-07 EP disclosed
US-20060020337-A1 Process for making silicone intraocular lens with blue light absorption properties BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC) (HU) 2006-01-26 US disclosed
US-20060020340-A1 Process for making silicone intraocular lens with blue light absorption properties LAI YU-CHIN 2006-01-26 US disclosed
WO-2005026266-A1 NOVEL REACTIVE YELLOW DYES USEFUL FOR OCULAR DEVICES BAUSCH & LOMB INCORPORATED (US) 2005-03-24 WO disclosed
WO-2005025632-A1 INTRAOCULAR LENS WITH BLUE LIGHT ABSORPTION PROPERTIES AND PROCESS BAUSCH & LOMB INCORPORATED (US) 2005-03-24 WO disclosed
US-20050055091-A1 Process for making silicone intraocular lens with blue light absorption properties BAUSCH & LOMB INCORPORATED 2005-03-10 US disclosed
US-20050054797-A1 Novel reactive yellow dyes useful for ocular devices SOLTA MEDICAL, INC. 2005-03-10 US disclosed
US-5863701-A POLYMERS FOR PHOTORESISTS USED FOR PRINTING PLATES AND CIRCUIT BOARDS OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-01-26 US disclosed
US-5780566-A Polymers containing protected styrene and unprotected hydroxybenzyl (meth)acrylamides OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1998-07-14 US disclosed
EP-0709410-A2 Polymers OCG Microelectronic Materials, Inc. (US) 1996-05-01 EP disclosed
US-5328973-A Acid labile protecting groups are cleaved by strong acid formed by ultraviolet radiation, solubility of polymer is changed HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-12 US disclosed