Phosphoric Acid

Phosphoric Acid

SCHEMBL43280

CC(=O)C(O)O.O=P(O)(O)O

nearest known ligand 0.38

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.38
MMP2 P08253 2/20 0.33
MMP8 P22894 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 1/20 0.33
MMP3 P08254 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.31
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
GABRR1 P24046 1/20 0.31
GABBR2 O75899 1/20 0.31
GABBR1 Q9UBS5 1/20 0.31
LAP3 P28838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL5485139 1.00 CA2 (0.38) CA2MMP2MMP8CA12CA1
Phosphoric Acid SCHEMBL4423473 1.00 CA2 (0.38) CA2MMP2MMP8CA12CA1
Phosphoric Acid SCHEMBL6407186 1.00 CA2 (0.38) CA2MMP2MMP8CA12CA1
Phosphoric Acid SCHEMBL20798015 1.00 CA2 (0.38) CA2MMP2MMP8CA12CA1
Phosphoric Acid SCHEMBL28701485 0.97 CA2 (0.35) CA2MMP2MMP8CA12CA1
Pyruvate SCHEMBL4422058 0.88 TP53 (0.32) CA2TP53TSHRTHPOFFAR3
Pyrophosphoric Acid SCHEMBL10768846 0.86 FDPS (0.53)
Methylglyoxal SCHEMBL20913197 0.86 ALDH1A1 (0.30)
Pyrophosphoric Acid SCHEMBL10876382 0.86 FDPS (0.53)
SCHEMBL71 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8491 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20260035705-A1 ENGINEERED MICROORGANISMS WITH G3P ->3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY AGAIN BIO APS (DK) 2026-02-05 US claimed
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
EP-4655386-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF CARBON-CONTAINING NON-NITROGEN COMPOUNDS Fertis India Pvt Ltd (IN) 2025-12-03 EP claimed
EP-4615963-A1 GENETICALLY MODIFIED BENZYLISOQUINOLINE ALKALOID-PRODUCING HOST CELLS WITH MODIFIED EFFLUX TRANSPORTER GENE EXPRESSION River Stone Biotech ApS (DK) 2025-09-17 EP claimed
EP-4612179-A1 BISPECIFIC ANTIBODIES AGAINST CD3 AND CD20 FOR TREATING RICHTER'S SYNDROME Genmab A/S (DK) 2025-09-10 EP claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
US-20250231190-A1 ENHANCED FLUORESCENCE SIGNAL THROUGH THE APPLICATION OF AROMATIC ADDITIVES ONTO THE MICROSCOPY SAMPLE FOR STANDARD FLUORESCENCE, FLUORESCENCE MICROSCOPY AND COMBINED FLUORESCENCE MALDI MICROSCOPY/IMAGING THE JOHNS HOPKINS UNIVERSITY 2025-07-17 US claimed
EP-0035521-A4 METHOD OF DETERMINING A SUBSTRATE IN A SAMPLE. PRINCE CHARLES HOSPITAL DEV CT (AU) 1982-02-16 EP claimed
US-4309502-A ANALYSIS FOR BOTH IN SINGLE CUVETTE BECKMAN INSTRUMENTS, INC. (US) 1982-01-05 US claimed
EP-0035521-A1 METHOD OF DETERMINING A SUBSTRATE IN A SAMPLE THE PRINCE CHARLES HOSPITAL DEVELOPMENT CENTRE TRUST (AU) 1981-09-16 EP claimed
EP-0030718-A1 Method and reagents for the determination of triglycerides Roche Diagnostics GmbH (DE) 1981-06-24 EP claimed
WO-1981000725-A1 METHOD OF DETERMINING A SUBSTRATE IN A SAMPLE CHARLES HOSPITAL DEV (AU) 1981-03-19 WO claimed
US-4245041-A Triglycerides assay and reagents therefor AMERICAN MONITOR CORPORATION (US) 1981-01-13 US claimed
US-4242446-A Method for determining a substance in a biological fluid and reagent combination for use in the method COULTER ELECTRONICS, INC. (US) 1980-12-30 US claimed
US-4209589-A Enzymatic process for preparing [γ-32 P]-labeled nucleotides VANDERBILT UNIVERSITY (US) 1980-06-24 US claimed
US-4151043-A Enzyme determination method SIGMA CHEMICAL COMPANY (US) 1979-04-24 US claimed
US-4001089-A METHOD FOR DETERMINATION OF TRIGLYCERIDES AND GLYCEROL THE DOW CHEMICAL COMPANY (US) 1977-01-04 US claimed