Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788298 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10LMNASLC1A3 | |
| SCHEMBL13087404 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10LMNASLC1A3 | |
| SCHEMBL23777420 | 0.87 | SLC1A3 (0.39) | ALDH1A1HSD17B10LMNASLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL27938118 | 0.85 | SLC1A3 (0.38) | ALDH1A1HSD17B10LMNASLC1A3SLC1A2 | |
| SCHEMBL8321449 | 0.82 | HSD17B10 (0.42) | ALDH1A1TSHRHSD17B10LMNASLC1A3 | |
| SCHEMBL28363179 | 0.82 | SLC1A2 (0.39) | ALDH1A1TSHRHSD17B10LMNASLC1A3 | |
| SCHEMBL678279 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10LMNASLC1A1 | |
| SCHEMBL28788296 | 0.81 | NAAA (0.35) | ALDH1A1SLC1A3SLC1A2SLC1A1ALOX15 | |
| SCHEMBL29090621 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10LMNASLC1A1 | |
| SCHEMBL998406 | 0.81 | ALOX15 (0.44) | ALDH1A1TSHRHSD17B10LMNASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021469-A1 | AMIDASES AND METHODS OF THEIR USE | CODEXIS, INC. (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021469-A1 | AMIDASES AND METHODS OF THEIR USE | ANPEP, DNPEP, NAAA | ALDH1A1 4716/4885TSHR 1653/4885HSD17B10 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.