SCHEMBL678279

SCHEMBL678279

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nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.35
SLC1A1 P43005 1/20 0.32
GRIK1 P39086 1/20 0.30
SLC7A5 Q01650 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29090621 1.00 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10TDP1LMNA
Acetic Acid SCHEMBL27618719 0.96 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL2158686 0.85 SLC1A1 (0.37) SLC1A1
SCHEMBL1396066 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL2400319 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL7748632 0.82 SLC1A1 (0.30) SLC1A1
SCHEMBL432874 0.81 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL28788298 0.81 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL13087404 0.81 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL7092900 0.79 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110381944-A Substances for the treatment of fatty liver related disorders 斯堪的比奥疗法有限公司 2019-10-25 CN claimed
CN-110088615-A Detection and quantitative mass spectrometric determination method for renal function metabolin 梅塔博隆股份有限公司 2019-08-02 CN claimed
CN-109563127-A Diagnostic method, therapeutic agent and use thereof 麦特博隆股份有限公司 2019-04-02 CN claimed
CN-109328018-A Adjust the composition and method of the intracorporal phosphorus of companion animals or enzyme 雀巢产品技术援助有限公司 2019-02-12 CN claimed
CN-109298115-A A variety of metabolin quantitative detecting methods and metabolism chip in biological sample 深圳市绘云生物科技有限公司 2019-02-01 CN claimed
CN-106362578-A Flue gas treatment method 徐明好 2017-02-01 CN claimed
EP-1750126-B1 METHOD AND APPARATUS FOR ANALYZING AMINOFUNCTIONAL COMPOUND AJINOMOTO KK (JP) 2015-09-16 EP claimed
EP-2858638-A1 ALLOSTERIC CHAPERONES AND USES THEREOF Fondazione Telethon (IT) 2015-04-15 EP claimed
WO-2013182652-A1 ALLOSTERIC CHAPERONES AND USES THEREOF FONDAZIONE TELETHON (IT) 2013-12-12 WO claimed
CN-101437507-A Oral preparation for sleep induction and oral preparation for improving stress insomnia FANCL CORP (JP) 2009-05-20 CN claimed
CN-101385857-A Novel nano preparation with stable protein and preparation method and use thereof UNIV CHINA PHARMA (CN) 2009-03-18 CN claimed
US-5008372-A Reacting with anhydrous trifluoroacetic acid CORNELL RESEARCH FOUNDATION, INC. (US) 1991-04-16 US claimed
EP-0142487-B1 NOVEL ATRIAL PEPTIDES WASHINGTON UNIVERSITY (US) 1990-01-03 EP claimed
EP-0142487-A2 Novel atrial peptides WASHINGTON UNIVERSITY (US) 1985-05-22 EP claimed
JP-11299491-A None JP disclosed
US-20250339370-A1 PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS AVANTOR PERFORMANCE MATERIALS, LLC (US) 2025-11-06 US disclosed
EP-4416135-A1 HERBICIDES AND USE THEREOF Projini Agchem Ltd (IL) 2024-08-21 EP disclosed
EP-0142487-B1 NOVEL ATRIAL PEPTIDES WASHINGTON UNIVERSITY (US) 1990-01-03 EP disclosed
EP-0142487-A2 Novel atrial peptides WASHINGTON UNIVERSITY (US) 1985-05-22 EP disclosed
US-4389343-A POLYPEPTIDES HOFFMANN-LA ROCHE INC. (US) 1983-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339370-A1 PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS AADAT, KYNU, PNISR ALDH1A1 3256/4885TSHR 3639/4885HSD17B10 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.