Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146558 | 0.98 | KIF11 (0.46) | SLC6A2KIF11TSHRFGF23LMNA | |
| SCHEMBL5144847 | 0.93 | FGF23 (0.47) | SLC6A2KIF11TSHRFGF23LMNA | |
| SCHEMBL2882525 | 0.88 | KIF11 (0.50) | SLC6A2KIF11TSHRFGF23LMNA | |
| SCHEMBL5146537 | 0.77 | KIF11 (0.48) | KIF11TSHRNISCHKDM4E | |
| SCHEMBL2874345 | 0.75 | KIF11 (0.50) | SLC6A2KIF11SIGMAR1 | |
| SCHEMBL5147795 | 0.74 | KIF11 (0.50) | KIF11TSHRNISCHKDM4E | |
| SCHEMBL3423876 | 0.74 | KIF11 (0.70) | KIF11TSHRLMNATYRSMN1; SMN2 | |
| SCHEMBL26915 | 0.74 | KIF11 (0.70) | KIF11TSHRLMNATYRSMN1; SMN2 | |
| SCHEMBL10703006 | 0.73 | HPGD (0.46) | LMNASMN1; SMN2NISCHMAPTTDP1 | |
| SCHEMBL22418954 | 0.72 | ACMSD (0.42) | SLC6A2KIF11TSHRFGF23LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817784-B | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES CO., LTD. (JP) | 2012-02-01 | — | — | CN | disclosed |
| CN-101817784-A | Ethene derivatives and the pesticides that contains this derivative | NISSAN CHEMICAL IND LTD | 2010-09-01 | — | — | CN | disclosed |
| US-7566683-B2 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| CN-101472924-A | KV1.5 potassium channel inhibitors | WYETH CORP (US) | 2009-07-01 | — | — | CN | disclosed |
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| WO-2007100161-A1 | METHOD FOR PREFERENTIAL PRODUCTION OF GEOMETRIC ISOMERS AND ISOLATION METHOD | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-09-07 | — | — | WO | disclosed |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
| US-7037880-B2 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| CN-1763003-A | Ethylene derivatives and pesticides containing the same | NISSAN CHEMICAL IND LTD (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1227229-C | Ethylene derivatives and pesticides containing the same | NISSAN CHEMICAL IND LTD (JP) | 2005-11-16 | — | — | CN | disclosed |
| EP-1360901-A1 | 2,3-cyclic substituted derivatives of 3-hydroxyacrolein and 3-hydroxyacrylic acid as pesticides | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-6642234-B1 | Insecticides, acaricides, nematocides, herbicides and fungicides, | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-0913392-B1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6462049-B1 | LOW TOXICITY AND PERSISTENT INSECTICIDES AND FUNGICIDES; PREVENTING ATTACHMENT OF AQUATIC ORGANISMS; ECOSYSTEM FRIENDLY; NONPOLLUTING | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-1142882-A9 | ACRYLONITRILE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2002-10-02 | — | — | EP | disclosed |
| CN-1333759-A | Acrylonitrile compounds | NISSAN CHEMICAL IND LTD (JP) | 2002-01-30 | — | — | CN | disclosed |
| EP-1142882-A1 | ACRYLONITRILE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6063734-A | AGRICULTURAL CHEMICALS, AGENTS FOR PREVENTING ATTACHMENT OF AQUATIC ORGANISMS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| CN-1216530-A | Ethylene derivatives and pesticides containing the same | NISSAN CHEMICAL IND LTD (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0913392-A1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | KCNA5, KCNH1, KCNK5 | SLC6A2 2171/4885KIF11 862/4885TSHR 1447/4885 |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | DDT, ECE1, EBPL | SLC6A2 4552/4885KIF11 3041/4885TSHR 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.