Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | PTPRC | P08575 | 3/20 | 0.47 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262386 | 0.87 | PTGS2 (0.52) | ERN1RAB9APOLBPTGS2PTPRC | |
| SCHEMBL31098731 | 0.86 | ERN1 (0.67) | ERN1POLBPTPRCS100A4BCHE | |
| SCHEMBL12798324 | 0.86 | ERN1 (0.67) | ERN1POLBPTPRCS100A4BCHE | |
| SCHEMBL5511292 | 0.84 | ERN1 (0.53) | ERN1RAB9APOLBPTGS2PTPRC | |
| SCHEMBL18094643 | 0.83 | TDP2 (0.49) | RAB9APTGS2PTPRCALDH1A1NPC1 | |
| SCHEMBL16586874 | 0.81 | ALOX5 (0.43) | ERN1RAB9APOLBPTGS2ALDH1A1 | |
| SCHEMBL6391559 | 0.80 | PTGS2 (0.69) | RAB9APOLBPTGS2PTPRCS100A4 | |
| SCHEMBL28207049 | 0.80 | PTGS2 (0.73) | RAB9APOLBPTGS2PTPRCS100A4 | |
| SCHEMBL7137309 | 0.80 | ERN1 (0.52) | ERN1RAB9APOLBPTGS2ELANE | |
| SCHEMBL7907202 | 0.79 | ALDH1A1 (0.51) | ERN1POLBPTPRCS100A4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010020104-A1 | Process for preparing substituted benzyl compounds and toluene derivatives | CLARIANT GMBH | 2001-09-06 | — | — | US | disclosed |
| EP-1127861-A1 | Method to synthesise substituted benzyl and toluene compounds | Clariant GmbH (DE) | 2001-08-29 | — | — | EP | disclosed |
| US-5994563-A | THIOPHENE DERIVATIVES, IMMUNOSUPPRESSANTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1999-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020104-A1 | Process for preparing substituted benzyl compounds and toluene derivatives | NISCH, TBCB, NBAS | ERN1 3489/4885RAB9A 1085/4885POLB 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.