SCHEMBL4329150

SCHEMBL4329150

CCCC1(C)OC1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 12/20 0.47
MAOA P21397 12/20 0.47
MAOB P27338 12/20 0.47
DRD2 P14416 2/20 0.40
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
CHRM5 P08912 2/20 0.37
CHRM1 P11229 2/20 0.37
CHRM3 P20309 2/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
DRD1 P21728 1/20 0.37
DRD4 P21917 1/20 0.37
DRD5 P21918 1/20 0.37
DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28887354 0.78 ALDH1A1 (0.46) KDM1AMAOAMAOBCHRM2CHRM4
SCHEMBL4089888 0.78 ALDH1A1 (0.46) KDM1AMAOAMAOBCHRM2CHRM4
SCHEMBL4386500 0.78 ALDH1A1 (0.46) KDM1AMAOAMAOBCHRM2CHRM4
SCHEMBL11424700 0.77 MAOA (0.44) KDM1AMAOAMAOBCHRM2CHRM4
SCHEMBL11699378 0.74 KDM1A (0.45) KDM1AMAOAMAOBDRD2CHRM2
SCHEMBL5955814 0.72 KDM1A (0.43) KDM1AMAOAMAOBCHRM2CHRM4
SCHEMBL3972334 0.72 KDM1A (0.43) KDM1AMAOAMAOBCHRM2CHRM4
SCHEMBL17660056 0.72 KDM1A (0.43) KDM1AMAOAMAOBCHRM2CHRM4
SCHEMBL11833585 0.72 KDM1A (0.39) KDM1AMAOAMAOBDRD2MAPT
SCHEMBL11438823 0.72 MAOA (0.39) KDM1AMAOAMAOBDRD2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815007-B2 Alkoxylated polyamines and polyetheramine polyol compositions for foam control ETHOX CHEMICALS, LLC (US) 2014-08-26 US disclosed
US-20120238483-A1 ALKOXYLATED POLYAMINES AND POLYETHERAMINE POLYOL COMPOSITIONS FOR FOAM CONTROL Ethox Chemicals, LLC. (US) 2012-09-20 US disclosed
US-8193144-B2 Alkoxylated polyamines and polyetheramine polyol compositions for foam control ETHOX CHEMICALS LLC (US) 2012-06-05 US disclosed
US-20090149369-A1 Alkoxylated polyamines and polyetheramine polyol compositions for foam control TANNER JAMES T 2009-06-11 US disclosed
WO-2009045408-A1 ALKOXYLATED POLYAMINES AND POLYETHERPOLYAMINE POLYOL COMPOSITIONS FOR FOAM CONTROL ETHOX CHEMICALS, LLC (US) 2009-04-09 WO disclosed
US-4186255-A POLYURETHANE CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1980-01-29 US disclosed
US-4136240-A METALLIC QUATERNARY AMMONIUM CARBOXYLATES AS POLYISOCYANURATE CATALYSTS TEXACO DEVELOPMENT CORPORATION (US) 1979-01-23 US disclosed
US-4075130-A DIAMINES, TRIAMINES TEXACO DEVELOPMENT CORPORATION (US) 1978-02-21 US disclosed
US-4060501-A Novolak derivatives as defoamers TEXACO DEVELOPMENT CORPORATION (US) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149369-A1 Alkoxylated polyamines and polyetheramine polyol compositions for foam control SMOX, SGMS1, SGMS2 KDM1A 566/4885MAOA 317/4885MAOB 771/4885
US-20120238483-A1 ALKOXYLATED POLYAMINES AND POLYETHERAMINE POLYOL COMPOSITIONS FOR FOAM CONTROL SMOX, SGMS1, SGMS2 KDM1A 566/4885MAOA 317/4885MAOB 771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.