SCHEMBL4329276

SCHEMBL4329276

Nc1ccc(Oc2ccc(C3(c4ccc(Oc5ccc(N)cc5)cc4)CC=CC=C3c3ccccc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.45
ALDH1A1 P00352 8/20 0.41
MAPT P10636 6/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
LMNA P02545 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
NCOA1 Q15788 1/20 0.40
NCOA3 Q9Y6Q9 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
NLRP3 Q96P20 1/20 0.39
CYP3A4 P08684 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
MITF O75030 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
NLRP1 Q9C000 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634495 0.81 OPRM1 (0.32) MAOAMEN1KMT2ACYP2C9MAOB
Biphenyl SCHEMBL28511221 0.79 ALDH1A1 (0.33) MAOAALDH1A1MAOBTAAR1
SCHEMBL6067737 0.76 MAOA (0.37) MAOAALDH1A1MAPTMEN1KMT2A
Biphenyl-4-Amine SCHEMBL28258675 0.68 MAOA (0.77) MAOAALDH1A1MAPTMEN1KMT2A
SCHEMBL553858 0.68 MAOA (0.77) MAOAALDH1A1MAPTMEN1KMT2A
Biphenyl SCHEMBL20395915 0.68 MAOA (0.77) MAOAALDH1A1MAPTMEN1KMT2A
SCHEMBL4980978 0.68 MAOA (0.77) MAOAALDH1A1MAPTMEN1KMT2A
SCHEMBL28815366 0.66 CYP3A4 (0.31) MAOACYP3A4TDP1MAOBTAAR1
SCHEMBL7174117 0.66 SMN1; SMN2 (0.34) KMT2ASMN1; SMN2
SCHEMBL9578203 0.66 ALDH1A1 (0.47) MAOAALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615260-B2 Active-matrix liquid crystal display HITACHI, LTD. (JP) 2009-11-10 US disclosed
US-20050012884-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2005-01-20 US disclosed
EP-0806698-B1 In-plane switching-mode active-matrix liquid crystal display HITACHI LTD (JP) 2005-01-12 EP disclosed
US-6756089-B2 MULTILAYER; POLYAMIDEIMIDE COPOLYMER HITACHI, LTD. (JP) 2004-06-29 US disclosed
US-20010046569-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2001-11-29 US disclosed
US-6242060-B1 MULTILAYER HITACHI, LTD. (JP) 2001-06-05 US disclosed
EP-0806698-A1 Active-matrix liquid crystal display HITACHI, LTD. (JP) 1997-11-12 EP disclosed