Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 3/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | MDH1 | P40925 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329968 | 0.87 | SMPD1 (0.46) | SMPD1ENPP1KMT2ACA2SMN1; SMN2 | |
| SCHEMBL4334952 | 0.86 | ENPP1 (0.53) | ENPP1KMT2ACA2SMN1; SMN2THRA | |
| SCHEMBL5314659 | 0.83 | GPR17 (0.49) | KMT2AATMGPR17P2RY2 | |
| SCHEMBL4326069 | 0.80 | KMT2A (0.48) | ENPP1KMT2AATMSMN1; SMN2GPR17 | |
| SCHEMBL5316845 | 0.78 | GSK3B (0.46) | ENPP1KMT2ATHRATHRB | |
| SCHEMBL3621448 | 0.77 | CA2 (0.54) | ENPP1CA2SMN1; SMN2CA12CA1 | |
| SCHEMBL7860030 | 0.76 | CYP4F2 (0.49) | THRATHRB | |
| SCHEMBL872966 | 0.74 | GPR17 (0.50) | ENPP1KMT2AATMGPR17P2RY2 | |
| SCHEMBL4326703 | 0.74 | MEN1 (0.59) | ENPP1KMT2ACA2SMN1; SMN2CA12 | |
| SCHEMBL5051428 | 0.73 | THRB (0.60) | SMPD1KMT2APLA2G4BTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |