Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MDH1 | P40925 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330115 | 0.87 | SMPD1 (0.43) | SMPD1ENPP1CA2SMN1; SMN2MDH1 | |
| SCHEMBL4326703 | 0.85 | MEN1 (0.59) | ENPP1CA2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4648365 | 0.80 | MAOB (0.56) | MAOBALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL3621448 | 0.80 | CA2 (0.54) | ENPP1CA2SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4332039 | 0.77 | KMT2A (0.55) | MAOBENPP1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5314017 | 0.77 | MAOB (0.47) | SMPD1MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL5312870 | 0.76 | MAOB (0.49) | MAOBMAOASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL22187276 | 0.76 | MAPT (0.55) | ENPP1CA2SMN1; SMN2HTTMEN1 | |
| SCHEMBL29673517 | 0.76 | MAPT (0.55) | ENPP1CA2SMN1; SMN2HTTMEN1 | |
| SCHEMBL4334952 | 0.74 | ENPP1 (0.53) | ENPP1CA2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |